Apr 14, 2025 · The commonly used Cockcroft-Gault method may result in excessive chemotherapy dosing — with potentially dire implications.

Apr 20, 2012 · The MDRD and CKD-EPI equations estimate the GFR directly, whereas the Cockcroft-Gault equation estimates creatinine clearance (CrCl). While CrCl is the parameter most often used in …

In addition, we compared the Cockcroft-Gault using TBW, IBW, FFW, and LBW with the MDRD4 and Salazar-Corcoran equations for estimating CL cr in obese patients.

The common use of the Cockcroft-Gault equation suggests that it will remain the method of choice for drug dosing in patients with renal impairment. In contrast, the MDRD4 equation is likely to ...

Does the Cockcroft-Gault equation provide a superior estimation of creatinine clearance in underweight patients compared to other equations?

Conclusion An LBW estimate, based on TBW and BMI, incorporated into the Cockcroft-Gault equation provided an unbiased, relatively precise, accurate, and clinically practical estimate of 24-hour ...

All three equations were biased in their estimation of CL cr. Use of MDRD4 and IBW in the Cockcroft-Gault equation underestimated CL cr, while the Salazar-Corcoran equation and use of TBW or ABW ...

This creates a bias in favor of the MDRD 4 equation in estimating the GFR, as the use of ABW in the Cockcroft–Gault equation could potentially lead to an overestimation of CL cr in obese patients.

Cockcroft–Gault Versus MDRD4 Equation Although the MDRD GFR study group has indicated that the MDRD4 equation may be more accurate than the Cockcroft–Gault equation as a predictor of GFRs, it ...

3 days ago · Today on Medscape : Get the latest medical news, clinical trial coverage, drug updates, journal articles, CME activities & more on Medscape. A free resource for physicians.