Transfer RNAs (tRNAs) perform a critical function in the creation of new proteins. Messenger RNA (mRNA) molecules are transcribed from active genes and are 'read' by cellular machinery, which adds new ...

For disorders driven by a known genetic component, research understandably focuses on developing a drug targeting that genetic signature. When that works, the outcome benefits patients but the end ...

For years, scientists have been puzzled by the presence of short stretches of genetic material floating inside a variety of cells, ranging from bacteria to mammals, including humans. These fragments ...

Aminoacyl-tRNA synthetases (aaRSs) are ancient and evolutionary conserved enzymes catalyzing the formation of aminoacyl-tRNAs, that are used as substrates for ribosomal protein biosynthesis. In ...

Yeast mutants with decreased expression of a tRNA Tyr gene were obtained by selection for functional inactivation of the tyrosine-inserting ochre suppressor SUP4 and subsequent screening for ...

Ribonucleic acid (RNA) molecules are present in all living cells, with different types of RNA having different jobs. For example, messenger RNA is copied from DNA and carries instructions on how to ...

Deep in the protein translation machinery are cogs known as transfer RNAs, or tRNAs. Actually, they may be more than mere cogs, say scientists at the University of Chicago. Like other components of ...

On Tuesday, Flagship Pioneering, the major investor behind Moderna, announced yet another addition to their portfolio of RNA-curious companies. Following a year of hype around mRNA, a new company, ...

The chemical steps involved in an important cellular modification process that adds a chemical tag to some RNAs has been revealed in a new study. Interfering with this process in humans can lead to ...

With a move into Lilly Gateway Labs in Boston’s Seaport District, privately held Tevard Biosciences Inc. is ramping up development of its transfer RNA (tRNA)-based therapies to cure everything from ...