Throughout this timeframe, technological developments spawning next-generation sequencing were leading to dramatic decreases in costs and turnaround times. Alternative business models among new ...

Immunohistochemistry (IHC) has continually evolved alongside technological and scientific advances. Because scientists constantly develop and modify their IHC techniques to better answer modern ...

Listen in as our scientific expert, Tom Ruyle, discusses how to optimize your IHC protocol and reviews top troubleshooting tips. How to choose an antibody for IHC How to optimize your protocol for the ...

Immunohistochemistry protocols, which utilize antibodies to visualize proteins in tissue sections, have many steps that need optimization to prevent nonspecific background effects, artifacts, or ...

Our core is staffed by experts in immunohistochemistry (IHC), in situ hybridization (ISH), and multiplex fluorescence using multiple antibodies and/or probes. We offer routine protocols in these ...

COLD SPRING HARBOR, N.Y. (Wed., Jan. 2, 2008) – This month’s release of Cold Spring Harbor Protocols highlights methods that permit scientists to observe protein dynamics in chromosomes and embryos.

Investigators who are writing grants can find below a description of the Experimental Histopathology shared resource and its services for their grant applications. Descriptions of the overall Fred ...

From our in-house laboratory rodent colony, tissues from healthy sentinel mice were collected at scheduled necropsy, fixed overnight in 10% neutral-buffered formalin or 100% ethanol, and routinely ...

Breast carcinoma is the leading cause of death in women with over 300 000 deaths annually worldwide (Pisani et al, 1999a, 1999b). Axillary lymph node (ALN) status is one of the most important ...

Despite widespread provision of Lynch syndrome (LS) screening programs, questions remain about the most effective and efficient protocol for LS case finding. The purpose of this study was to explore ...