In this collection we highlight a selection of articles from 2025, which top the list of the journal’s most cited, downloaded and most shared (including press coverage, blogs, X, Facebook and Weibo).

Viruses and cancers are deeply intertwined. Globally, one in ten new cancer cases arises in the context of chronic viral infections, with human papillomaviruses (HPVs) and hepatitis B and C viruses ...

Cats are not just beloved companions; they are emerging as key "research partners" in unraveling viral cancer mechanisms. A ...