CRISPR-Cas12a technology is emerging as a powerful tool for infectious disease diagnostics, combining precision with speed and portability. New one-pot and amplification-free systems are delivering ...

When COVID first hit, waiting days for laboratory results from an ultrasensitive polymerase chain reaction (PCR) test was commonplace. Faster tests usable by anyone, anywhere, later became widely ...

Pneumocystis jirovecii pneumonia (PJP) is the most common fungal pneumonia in children. But current diagnostic methods can take days an require an invasive bronchoscopy procedure. Now, a new ...

Researchers have developed a fast, specific and reliable test for mpox infection, combining CRISPR/Cas12a and nanopore sensing. Research presented at the 68th Biophysical Society Annual Meeting (10-14 ...

Tulane University researchers have developed a CRISPR-based test that diagnoses Pneumocystis jirovecii pneumonia (PJP) - a life-threatening fungal infection primarily affecting children and ...

At the start of the SARS-CoV-2 pandemic people who felt unwell had to join long queues for lab-based PCR tests and then wait for two days to learn if they were infected with the COVID-19 virus or not.

The rapid spread of animal diseases and pathogen evolution have long posed significant threats to the healthy development of animal husbandry. Traditional nucleic acid detection methods such as PCR ...

Since the landmark discovery that a bacterial defense mechanism could be repurposed into programmable “molecular scissors,” CRISPR-Cas9 gene-editing technology has undergone a major evolution. Over ...

The coronavirus disease 2019 (COVID-19) pandemic was one of the most serious public health calamities in the last decade, causing global morbidity and mortality in the millions. The emergence of ...

Tulane University researchers have developed a CRISPR-based test that diagnoses Pneumocystis jirovecii pneumonia (PJP) — a life-threatening fungal infection primarily affecting children and ...