Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

Researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. University ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in ...

Double-stranded DNA viruses come in two main flavors, classified by their shapes. One contains large and giant DNA viruses that attack complex cells but also includes some viruses that are much ...

The first peer-reviewed journal in the field of human gene therapy, providing all-inclusive coverage of the research, methods, and clinical developments that are driving today's explosion of gene ...

Following a double-strand DNA break, an enzyme called PARP1 helps hold the two strands together —like superglue— and creates a safe zone for other proteins to come repair the damage. We don’t exactly ...

For the first time, scientists have captured the exact moment DNA begins to unravel, shedding light on a fundamental chemical process that enables DNA to serve as the blueprint for life. A recent ...

The cold sore-causing Herpes Simplex Virus (HSV-1) hijacks human cells and reconfigures its DNA within just an hour after infection, according to a new study that may help tackle the pathogen. Viruses ...