Argatroban could revive the practice of acute anticoagulation for reducing disability after stroke, based on the EASE trial from China. In patients with acute ischemic stroke and early neurological ...

Recombinant hirudin (including lepirudin and desirudin) is excreted by the kidney, is the tightest-binding DTI, appears effective for PCI at measurable aPTTs, is approved for patients with HIT, and ...

Direct thrombin inhibitors prevent the conversion of fibrinogen into fibrin during the coagulation cascade and ultimately prevent the development of a thrombus. 11 Dabigatran etexilate was the first ...

A novel class of antithrombotic medication, the factor XIa inhibitors, has had a rocky start but is powering through phase III trials, which are now underway. MedPage Today sat down to discuss the ...

Potent new anticoagulants have been discovered in the genetic code responsible for the saliva of blood-sucking ticks. Anticoagulants, also known as blood thinners, help prevent unwanted blood clotting ...

Coadministration of dabigatran etexilate with the antiplatelet drug clopidogrel had no effect on dabigratran's anticoagulant activity as measured by ECT, activated partial thromboplastin time (aPTT), ...

Credit: Getty Images. Endo’s product is the only ready-to-use formulation of bivalirudin currently on the market. Endo International has announced the launch of Bivalirudin Injection in a ready-to-use ...

Andexanet alfa (Andexxa; AstraZeneca), compared with usual care, improves hemostasis in patients who have an intracranial bleed while taking a factor Xa inhibitor, according to top-line results of ...