Throughout the course of our lives, DNA can break in response to natural and environmental factors. However, our bodies have dedicated enzymes and pathways which can repair our broken DNA back ...

Cedars-Sinai researchers have created TY1, an experimental RNA-based drug that helps the body repair damaged DNA and restore injured tissue. The idea came from studying tiny molecular “messages” ...

Image showing polymerase theta and polymerase delta's physical association. CHAPEL HILL, N.C. – Our DNA is not indestructible. Throughout the course of our lives, DNA can break in response to natural ...

DNA can sustain serious injuries called double strand breaks, in which both strands of the helix snap. These breaks are among ...

Human cancers exhibit genomic instability and an increased mutation rate due to underlying defects in DNA repair. Cancer cells are often defective in one of six major DNA repair pathways, namely: ...

Scripps Research scientists have discovered how some tumors endure DNA damage, revealing a potential new way to target them. The DNA inside our cells is constantly exposed to damage, and one of the ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Mitochondria are often described as the cell’s power plants, but a wave of new research suggests their genetic material may ...

An elegant collaboration between researchers in the UK's two core-funded Medical Research Council Research Institutes, the Laboratory of Medical Sciences (LMS) in London and the Laboratory of ...

DNA Repair Pathways in Clinical Practice: Lessons From Pediatric Cancer Susceptibility Syndromes. If you have the appropriate software installed, you can download article citation data to the citation ...