The eukaryotic structural maintenance of chromosomes (SMC) complexes cohesin, condensin and the SMC5/6 complex organize chromosome structure through their association with DNA and influence a large ...

Human artificial chromosomes (HACs) could be useful tools for both understanding how mammalian chromosomes function and creating synthetic biological systems, but for the last 20 years, they have been ...

Leading synthetic biologists have shared hard-won lessons from their decade-long quest to build the world's first synthetic ...

New light has been shed on a novel histone acetyltransferase protein complex called ATAC. Acetyltransferases are enzymes that introduce a new acetyl functional group into histone proteins, a process ...

AMES, Iowa – A new study led by an Iowa State University scientist sheds light on how organisms have evolved to address imbalances in sex chromosomes. The study looks at a species of softshell turtle, ...

In a report published in the Proceedings of the National Academy of Sciences, researchers working at Florida State University (FSU), Baylor College of Medicine and the Broad Institute of Harvard and ...

The human Y chromosome, responsible for male sex determination, has forfeited 97% of its ancestral genes over the past 300 ...

Molecular biologists long thought that domains in the genome's 3D organisation control how genes are expressed. After studying highly rearranged chromosomes in fruit flies, EMBL researchers now reveal ...

Human chromosomes behave in much the same way as those of rodents, primates, and other close evolutionary cousins. But researchers don’t know whether those similarities might extend to distantly ...

The role of sex in human disease is a growing area of research. Although estrogen (in females) and androgens (in males) are often seen as possible causes for such differences, sex chromosomes, ...