An international research team has identified a previously overlooked factor that influences how antibodies neutralize ...

Mapping an antibody’s epitope, where it binds a target, can now be done in three dimensions, which optimizes the selection of application-specific antibodies When using antibodies in research or ...

Antibodies have transformed the way physicians treat patients with different pathologies. The next generation of monoclonal antibody (mAb) therapeutics in immuno-oncology have been optimized for ...

HIV-1 envelope glycoprotein (Env), a gp120–gp41 trimer, undergoes coordinated conformational changes that drive membrane fusion and allow immune evasion by transiently concealing ...

Antibody therapeutics are laboratory-made proteins designed to work like the body’s natural antibodies. They are widely used to treat diseases such as cancer by binding to specific targets, including ...

This article is based on a poster originally authored by Dillon Rinauro, Thomas Peplow, Phil Rawlins, Alec O'Keeffe, Corinne Tovey, Tayo Alleyne-Weir, James Craswell, Kartika Shetty, Michaela ...

UAB researchers discover that the immune system consistently targets the same region of mismatched HLA proteins after organ ...

Researchers from the Shenzhen Institutes of Advanced Technology (SIAT), Chinese Academy of Sciences, along with multiple collaborators, have developed a compact diagnostic platform that can evaluate ...

The global spread of Highly Pathogenic Avian Influenza (HPAI), particularly the H5N1 2.3.4.4b clade, underscores the urgent ...